What exactly is Melatonin? If you do a google search you will find endless articles describing it as hormone use for sleep. That is what most people
associate melatonin with as well. By the time you finish this article you will see that is much much more than the “sleep hormone”.
Melatonin is a hormone made naturally by your body. It is produced by the pineal
gland in the brain and is a metabolite of serotonin. But it is also found in other
areas, such as the eyes, bone marrow and gut. Melatonin works together with
your body’s circadian rhythm. The circadian rhythm is your body’s internal clock.
It lets you know when it’s time to sleep, wake and eat. Melatonin also helps
regulate your body temperature, blood pressure and hormone levels.
Melatonin levels start to rise in your body when it is dark outside, signaling to
your body that it is time to sleep. It also binds to receptors in the body and can help you relax. For instance, melatonin binds to receptors in the brain to help reduce nerve activity. In the eyes, it can help reduce dopamine levels, a hormone
that helps you stay awake. Although the exact way melatonin helps you fall
asleep is unclear, research suggests these processes can help you fall asleep.
Conversely, light suppresses melatonin production. This is one way that your
body knows it is time to wake up. As melatonin helps your body prepare for
sleep, people who don’t make enough of it at night can struggle to fall asleep.
There are many factors that may cause low levels at night. Stress, smoking,
exposure to too much light at night (including blue light), not getting enough
natural light during the day, shift work and aging all affect melatonin production.
Poor nutrition and digestive and assimilation issues can prevent adequate levels
of production.
Like most hormones, melatonin provides multiple benefits for the body. Melatonin
is best known for its effect on sleep. There are multiple studies that prove
melatonin does more than help with sleep. There is evidence that has an effect
on glycemic control through reducing glucose. It stimulates secretion of glucagon
which is important for glucose metabolism. Melatonin has been shown to
significantly decrease inflammatory markers such as CRP and IL6.
One study found melatonin administration may benefit diabetics with coronary
heart disease and doses of 10mg significantly increased plasma glutathione
levels. Glutathione is the bodies master antioxidant and is responsible for proper
detoxification. In a meta-analysis of random controlled trials doses of > 8mg
melatonin was found to lower blood lipids to include triglycerides and total
cholesterol. It was also noted to protect against LDL oxidation which is one of the
biggest contributors to atherosclerosis. Lower levels of melatonin was associated
with a greater risk of MI. Melatonin has been demonstrated to improve ulcer
healing and prevent harmful substances to induce damage to the intestinal
epithelium and may reduce the risk of intestinal permeability.
When I recommend melatonin, it is not just for sleep. It is time to get over all the superficial advertisements and explore the real benefits of this powerful and
under estimated hormone. I hope by reading this you too will continue to use it as a regular part of your health program.
Health and happiness,
Charlie
"God gave us the gift of life; it is up to us to give ourselves the gift of living well." - Voltaire
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